Reactions of (CO) 5MnSi (CH3) 3 with. alpha.-bromo carbonyl and related organic compounds. Facile reductive silylation

…, CA Lisensky, GD Vaughn, JA Gladysz

Index: Marsi, Marianne; Brinkman, Kerry C.; Lisensky, Carol A.; Vaughn, George D.; Gladysz, J. A. Journal of Organic Chemistry, 1985 , vol. 50, # 18 p. 3396 - 3401

Full Text: HTML

Citation Number: 5

Abstract

Results (1) Reactions of a-Halo Ketones and a-Halo Aldehydes. Reaction of a- bromocyclohexanone with 1.0 equiv of 1 for 3 h in acetonitrile at room temperature gave, as assayed by GLC, debrominated products cyclohexanone trimethylsilyl enol ether and cyclohexanone in a 81: 19 ratio and a combined yield of> 96%(entry 1, Table I). 9 A preparative reaction was conducted without solvent for 2 days at 50 OC (1.5 equiv of 1). ...