Advanced Synthesis & Catalysis

Catalytic Enantioselective Hydrophosphonylation of Aldehydes Using the Iron Complex of a Camphor??Based Tridentate Schiff Base [FeCl (SBAIB??d)] 2

R Boobalan, C Chen

Index: Boobalan, Ramalingam; Chen, Chinpiao Advanced Synthesis and Catalysis, 2013 , vol. 355, # 17 p. 3443 - 3450

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Citation Number: 14

Abstract

Abstract An iron (III)-Schiff base-catalyzed, highly enantioselective hydrophosphonylation of various aldehydes is described. Under the optimized reaction conditions, 5 mol% of the iron/camphor-based tridentate Schiff base complex [FeCl (SBAIB-d)] 2 produces high yields (up to 99%) of α-hydroxy phosphonates in excellent enantioselectivities (up to 99%). The merits of this catalytic system are an easily synthesizable catalyst, inexpensive starting ...

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