Estrogenic compounds determination in water samples by dispersive liquid–liquid microextraction and micellar electrokinetic chromatography coupled to mass spectrometry

Giovanni D’Orazio, María Asensio-Ramos, Javier Hernández-Borges, Salvatore Fanali, Miguel Ángel Rodríguez-Delgado

Index: J. Chromatogr. A. 1344 , 109-21, (2014)

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Abstract

• A NSM–MEKC–MS approach using APFO has been developed for the separation of 12 estrogens. • All parameters were carefully optimized, obtaining the separation in less than 11min. • A DLLME procedure was optimized for the extraction of the analytes from water samples. • The DLLME–MEKC–MS method was validated by recovery and calibration studies. • The matrix effect was statistically evaluated obtaining evident positive results.