Epigenetic regulation of microRNA expression in renal cell carcinoma
Miriam Schiffgen, Doris H. Schmidt, Alexander von Rücker, Stefan C. Müller, Jörg Ellinger
Index: Biochem. Biophys. Res. Commun. 436(1) , 79-84, (2013)
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Abstract
• microRNAs are silenced by histone acetylation. • 5-Aza-2′dC and SAHA induce microRNA re-expression. • 5-Aza-2′dC and SAHA are most efficient in combination.
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