Direct one-pot conversion of acylated carbohydrates into their alkylated derivatives under heterogeneous reaction conditions using solid NaOH and a phase transfer …
SK Madhusudan, G Agnihotri, DS Negi, AK Misra
Index: Madhusudan, Soni Kamlesh; Agnihotri, Geetanjali; Negi, Devendra S.; Misra, Anup Kumar Carbohydrate Research, 2005 , vol. 340, # 7 p. 1373 - 1377
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Citation Number: 50
Abstract
A convenient one-pot protocol for the direct conversion of acyl-protected carbohydrates into their alkylated counterparts has been developed by using alkyl halides in the presence of solid sodium hydroxide and a phase transfer catalyst. These economically convenient, mild, two-phase reaction conditions allow the preparation of a variety of monosaccharide intermediates for use in the synthesis of complex oligosaccharides.
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