Tetrahedron Letters

5H-3-oxa-Octafluoropentanesulfonyl fluoride: a novel and efficient condensing agent for esterification, amidation and anhydridization

Z Yan, W Tian, F Zeng, Y Dai

Index: Yan, Zhaohua; Tian, Weisheng; Zeng, Fanrong; Dai, Yanfeng Tetrahedron Letters, 2009 , vol. 50, # 23 p. 2727 - 2729

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Citation Number: 15

Abstract

The use of 5H-3-oxa-octafluoropentanesulfonyl fluoride (HCF2CF2OCF2CF2SO2F) as a novel and efficient condensing reagent for esterification of carboxylic acids with alcohols and amidation of carboxylic acids with amines in the presence of 1, 3-diazabicyclo [5.4. 0]- undec-7-ene (DBU) is reported. HCF2CF2OCF2CF2SO2F cannot serve as a condensing agent for anhydridization of carboxylic acids, however, HCF2CF2OCF2CF2SO2F/(CH3) ...

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