Efficient, Highly Stereoselective Synthesis of α-Keto-deoxy-D-glycero-D-galacto-nonulosonic Acid (KDN) Glycosides by Means of the 4, 5-O-Carbonate …

D Crich, C Navuluri

Index: Crich, David; Navuluri, Chandrasekhar Organic Letters, 2011 , vol. 13, # 23 p. 6288 - 6291

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Abstract

Abstract A 1-adamantyl thioglycoside derivative of KDN, derived from N-acetylneuraminic acid, carrying a 3, 4-O-carbonate protecting group is a highy efficient and α-selective KDN donor on activation with NIS and TfOH in dichloromethane and acetonitrile at− 78 C.