Solvolysis of some 1-(8α-ergolinyl)-3, 3-diethylureas and their salts

…, J Beneš, J Vachek, M Pešák, J Stuchlík…

Index: Cerny, Antonin; Benes, Jan; Vachek, Jaroslav; Pesak, Milan; Stuchlik, Josef; et al. Collection of Czechoslovak Chemical Communications, 1987 , vol. 52, # 5 p. 1331 - 1339

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Citation Number: 9

Abstract

Abstract Nine salts of 1-(8α-ergolinyl)-3, 3-diethylurea (II) were prepared and their solubility in water and the stability of the aqueous solutions at 60 and 100 C were studied. The main product of hydrolysis is 6-methyl-8α-aminoergoline IV. The urethan VII is formed in the ethanolic solution. Both decomposition products are also formed under long-term storage at+ 5 C. The course of hydrolysis of N-propyl homologue III is similar. The decomposition ...