Large-scale preparation of (+)-p-menth-2-ene-1, 8-diol, a key intermediate in the synthesis of Δ-9-tetrahydrocannabinol
JE Cabaj, JM Lukesh, RJ Pariza…
Index: Chang, Jay Hyok; Shin, Hyunik Organic Process Research and Development, 2008 , vol. 12, # 2 p. 291 - 293
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Citation Number: 8
Abstract
... figure Scheme 9. Overall plant process to produce 1. The diol produced using the described procedure was used ... Keys to the process were a high throughput rearrangement followed by epoxidation and an operationally simple epoxide opening with water in organic solvent. ...