Convenient preparation of bis-enones and bis-enoates from cycloalkenes

J Montgomery, AV Savchenko…

Index: Montgomery, John; Savchenko, Alexey V.; Zhao, Yunbo Journal of Organic Chemistry, 1995 , vol. 60, p. 5699 - 5701

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Citation Number: 15

Abstract

Bis-enones and bis-enoates have proven to be valuable intermediates in a variety of methods for the synthesis of carbocyclic ring systems. Most notable among these methods are tandem Michael addition reactions in which enoxy silanes,'Grignard reagents with catalytic copper iodide, 2 or lithium silyl amides3 add in a conjugate fashion to one enone moiety followed by cyclization of the kinetic enolate onto the second enone moiety. p, p- ...