A Stereoselective Synthesis of (Z)-3-Aryl and Alkylmethylidene-1H-isoindolin-1-ones
M Lamblin, A Couture, E Deniau, P Grandclaudon
Index: Lamblin, Marc; Couture, Axel; Deniau, Eric; Grandclaudon, Pierre Synthesis, 2006 , # 8 p. 1333 - 1338
Full Text: HTML
Citation Number: 14
Abstract
Abstract A series of Z-configured (hetero) aryl and alkylmethylideneisoindolin-1-ones has been efficiently prepared by treatment of N-methoxycarbonylisoindolin-1-ones with a base and reaction with selected aldehydes. The parent N-acylated isoindolin-1-ones have been assembled by a Parham-type cyclization of N-(2-iodoarylmethyl) dicarbamates.
Related Articles:
[Belluau, Vincent; Noeureuil, Pierre; Ratzke, Elfrun; Skvortsov, Aleksei; Gallagher, Sonia; Motti, Cherri Ann; Oelgemoeller, Michael Tetrahedron Letters, 2010 , vol. 51, # 36 p. 4738 - 4741]
SET photochemistry of phthalimide anion and its reactivity with hydrogen donors
[Sanchez-Sanchez, Cristobal; Perez-Inestrosa, Ezequiel; Garcia-Segura, Rafael; Suau, Rafael Tetrahedron, 2002 , vol. 58, # 36 p. 7267 - 7274]