Total synthesis and absolute stereochemistry of seragakinone A

A Takada, Y Hashimoto, H Takikawa…

Index: Takada, Akiomi; Hashimoto, Yoshimitsu; Takikawa, Hiroshi; Hikita, Katsuyoshi; Suzuki, Keisuke Angewandte Chemie - International Edition, 2011 , vol. 50, # 10 p. 2297 - 2301

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Citation Number: 33

Abstract

Seragakinone A (1), an antifungal and antibacterial compound, is produced by an unidentified marine fungus that is in symbiosis with rhodophyta Ceratodictyon spongiosum and was collected at Seragaki beach, Okinawa.[1] The intriguing structure of 1 features a densely oxygenated pentacyclic core having an angular prenyl substituent, and it was determined by using extensive spectroscopic studies and single-crystal X-ray analysis; ...