A Highly Enantioselective One??Pot Synthesis of Spirolactones by an Organocatalyzed Michael Addition/Cyclization Sequence
…, F Costantino, L Testaferri, M Tiecco…
Index: Sternativo, Silvia; Calandriello, Antonella; Costantino, Ferdinando; Testaferri, Lorenzo; Tiecco, Marcello; Marini, Francesca Angewandte Chemie - International Edition, 2011 , vol. 50, # 40 p. 9382 - 9385
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Citation Number: 33
Abstract
Spirocyclic compounds are attractive targets in organic synthesis because of their broad distribution in biologically active natural products and pharmaceuticals,[1] as well as their increasing use in a range of important chemical and technological processes, such as asymmetric synthesis and organic optoelectronics.[2] On this basis the development of novel methods for the construction of spirocyclic frameworks is of considerable importance, ...
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