Tetrahedron letters

4-(Trialkylsilyl) oxybut-2-ynals as dienophiles in the Diels–Alder synthesis of α-(hydroxymethyl) benzaldehydes

CF Morrison, DJ Burnell

Index: Morrison, Christopher F; Burnell Tetrahedron Letters, 2001 , vol. 42, # 42 p. 7367 - 7369

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Citation Number: 6

Abstract

The α-(hydroxymethyl) benzaldehyde derivative 2 has been synthesized by heating ynal 3 with diene 5, which produced the α-(silyloxymethyl) benzaldehyde 6 by a Diels–Alder/retro- Diels–Alder process, followed by methylation, thioacetalization, and removal of the silyl