Nouvelle voie de synthese des 1, 4-dihydroisoquinolein-3 (2H)-ones

S Kinate, L Chraïbi, M Soufiaoui

Index: Kitane, Said; Chraibi, Leila; Soufiaoui, Mohamed Tetrahedron, 1992 , vol. 48, # 41 p. 8935 - 8946

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Citation Number: 5

Abstract

The 1, 3-dipolar cycloaddition of arylazides with 1, 2-dihydro-isoquino line derivatives leads to new triazolinic adducts. The thermolysis of these latters followed to a hydrolysis conducts to 1, 4-dihydroisoquinolin-3 (2H)-oes. The structure of the adducts and other products are assigned. The regio and diastereospecificity of the cycloaddition reaction are discussed on the basis of 1H NMR data.