Practical, highly convergent, asymmetric synthesis of a selective PPARγ modulator

PE Maligres, GR Humphrey, JF Marcoux…

Index: Organic Process Research and Development, , vol. 13, # 3 p. 525 - 534

Full Text: HTML

Citation Number: 19

Abstract

... Organic Process Research & Development. ... Process Res. Dev. ... Acylation of indole 5 was accomplished using a slightly modified procedure from Okauchi and co-workers.(26) Treatment of indole 5 with Et 2 AlCl (1.2 equiv) and p-chlorobenzoyl chloride (1.2 equiv) in a mixture of ...