Degradation of neohesperidin dihydrochalcone by human intestinal bacteria

A Braune, W Engst, M Blaut

Index: Braune, Annett; Engst, Wolfram; Blaut, Michael Journal of Agricultural and Food Chemistry, 2005 , vol. 53, # 5 p. 1782 - 1790

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Citation Number: 35

Abstract

The degradation of neohesperidin dihydrochalcone by human intestinal microbiota was studied in vitro. Human fecal slurries converted neohesperidin dihydrochalcone anoxically to 3-(3-hydroxy-4-methoxyphenyl) propionic acid or 3-(3, 4-dihydroxyphenyl) propionic acid. Two transient intermediates were identified as hesperetin dihydrochalcone 4'-β-d-glucoside and hesperetin dihydrochalcone. These metabolites suggest that neohesperidin ...