Catalytic Asymmetric Claisen Rearrangement of Enolphosphonates: Construction of Vicinal Tertiary and All??Carbon Quaternary Centers

J Tan, CH Cheon, H Yamamoto

Index: Tan, Jiajing; Cheon, Cheol-Hong; Yamamoto, Hisashi Angewandte Chemie - International Edition, 2012 , vol. 51, # 33 p. 8264 - 8267

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Citation Number: 31

Abstract

The development of a one-step catalytic method for the enantioselective construction of contiguous tertiary and allcarbon quaternary centers is a challenging task but of great significance.[1, 2] Among the limited number of available approaches for the assembly of such sterically congested structures by a single transformation, the Claisen rearrangement, well-known as one of the most effective carbonÀ carbon bond-formation strategies, has ...