Search for surrogates: A study of endothelin receptor antagonist structure activity relationships

B Raju, I Okun, F Stavros, MF Chan

Index: Raju; Okun, Ilya; Stavros, Fiona; Chan, Ming Fai Bioorganic and Medicinal Chemistry Letters, 1997 , vol. 7, # 7 p. 933 - 938

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Citation Number: 10

Abstract

Download full text in PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... The aryloxymethylene group was used as a replacement for an ester or amide bond present in a series of ET A selective endothelin antagonists. The effect of such replacement on the binding affinity is described. ... The aryloxymethylene group was used as a replacement for an ...