Cross-coupling reactions of aryl pivalates with boronic acids

KW Quasdorf, X Tian, NK Garg

Index: Quasdorf, Kyle W.; Tian, Xia; Garg, Neil K. Journal of the American Chemical Society, 2008 , vol. 130, # 44 p. 14422 - 14423

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Citation Number: 231

Abstract

The first cross-coupling of acylated phenol derivatives has been achieved. In the presence of an air-stable Ni (II) complex, readily accessible aryl pivalates participate in the Suzuki− Miyaura coupling with arylboronic acids. The process is tolerant of considerable variation in each of the cross-coupling components. In addition, a one-pot acylation/cross-coupling sequence has been developed. The potential to utilize an aryl pivalate as a directing ...

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