Synthesis of fused chromene-1, 4-naphthoquinones via ring-closing metathesis and Knoevenagel-electrocyclization under acid catalysis and microwave irradiation

…, IMCB da Silva, VF Ferreira, SB Ferreira, FC da Silva

Index: Da Rocha, David R.; Mota, Kelly; Da Silva, Illana M.C.B.; Ferreira, Vitor F.; Ferreira, Sabrina B.; Da Silva, Fernando De C. Tetrahedron, 2014 , vol. 70, # 20 p. 3266 - 3270

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Citation Number: 7

Abstract

Abstract Two complementary methodologies involving olefin ring-closing metathesis and Knoevenagel-electrocyclization were utilized for the synthesis of α-xyloidones and fused chromene-1, 4-naphthoquinones 5f–n and 6. The latter methodology was performed under acid catalysis or microwave irradiation allowing the synthesis of α-xyloidones 5f–j in moderate to good yield, which could not be obtained via the Knoevenagel- ...