A novel class of sugar-based ether-linked-dispirooxindolo-pyrrolidines/pyrrolizidines through [3+ 2]-cycloaddition of azomethine ylides
A Hemamalini, S Nagarajan, TM Das
Index: Hemamalini, Arasappan; Nagarajan, Subbiah; Mohan Das, Thangamuthu Carbohydrate Research, 2012 , vol. 352, p. 12 - 17
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Citation Number: 8
Abstract
An efficient one-pot synthesis of novel sugar based dispirooxindolo-pyrrolidines/ pyrrolizidines has been accomplished by a [3+ 2]-cycloaddition. This method utilizes an azomethine ylide derived from isatin and sarcosine/l-proline, with an ether linked α-, β- unsaturated-β-C-glycosidic ketones as the dipolarophile. All these sugar-based heterocyclics were characterized by NMR (1H and 13C) and elemental analysis. ...
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