Synthesis of polyfluoroalkylated 1, 4-diazinols and 1, 4-oxazinols using polyfluoro-2, 3-epoxyalkanes32+ 13

LV Saloutina, AY Zapevalov, MI Kodess…

Index: Saloutina; Zapevalov; Kodess; Saloutin Journal of Fluorine Chemistry, 1998 , vol. 87, # 1 p. 49 - 55

Full Text: HTML

Citation Number: 13

Abstract

It has been found that the reactions of polyfluoro-2, 3-epoxyalkanes with ethylenediamine and 2-aminoethanol yield 2, 3-di (polyfluoroalkyl) 1, 5, 6-trihydro-1, 4-diazin-2-ols and 2, 3-di (polyfluoroalkyl)-5, 6-dihydro-1, 4-oxazin-2-ols, respectively. In the case of unsymmetrical oxiranes mixtures of regioisomeric heterocyclic compounds have been obtained. These reactions were found to give some byproducts—N, N′-bis (polyfluoroacyl) ...

Related Articles:

Phosphoramidite building blocks for efficient incorporation of 2′-O-aminoethoxy (and propoxy) methyl nucleosides into oligonucleotides

[Bobkov, Georgii V.; Mikhailov, Sergey N.; Van Aerschot, Arthur; Herdewijn, Piet Tetrahedron, 2008 , vol. 64, # 27 p. 6238 - 6251]

A highly stereoselective synthesis of 1-amino-2, 5-anhydro-1-deoxyhexitols via 2-trifluoromethyl-oxazolinium intermediates

[Norrild, Jens Chr.; Pedersen, Christian; Sotofte, Inger Carbohydrate Research, 1997 , vol. 297, # 3 p. 261 - 272]

More Articles...