Relative role of halogen bonds and hydrophobic interactions in inhibition of human protein kinase CK2α by tetrabromobenzotriazole and some C (5)-substituted …

R Wąsik, M Łebska, K Felczak…

Index: McHugh, Callum J.; Tackley, Daniel R.; Graham, Duncan Heterocycles, 2002 , vol. 57, # 8 p. 1461 - 1470

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Citation Number: 25

Abstract

... J. Phys. ... The observed effect of the volume of a ligand molecule pointed to its predominant role in inhibitory activity, indicating that presumed halogen ... its high electronegativity, is a very poor halogen bond acceptor but is a good acceptor from standard hydrogen bond donors.(8). ...