Tetrahedron letters

A total synthesis of polyether antibiotic (−)-A23187 (calcimycin)

DP Negri, Y Kishi

Index: Negri, David P.; Kishi, Yoshito Tetrahedron Letters, 1987 ,  vol. 28,  # 10  p. 1063 - 1066

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Citation Number: 35

Abstract

Download full text in PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... A total synthesis of (−)-A23187 (calcimycin) was accomplished by a convergent approach. The key step of synthesis was the stereospecific cyclization of the β-hydroxy ketone into the spiroketal under basic conditions. ... A total synthesis of (−)-A23187 (calcimycin) was accomplished ...