Synlett

A Simple and Efficient Procedure for the Synthesis of Ketone Di-sec-alkyl Acetals

F Ono, H Takenaka, Y Eguchi, M Endo, T Sato

Index: Ono, Fumiaki; Takenaka, Hirotaka; Eguchi, Yuko; Endo, Masato; Sato, Tsuneo Synlett, 2009 , # 3 p. 487 - 489

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Citation Number: 2

Abstract

Ketone di-sec-alkyl acetals are obtained in good to excellent yields by treatment of ketones with tri-sec-alkyl orthoformate and the corresponding alcohol in the presence of a catalytic amount of cerium(III) trifluoromethanesulfonate. ... In conclusion, the synthesis of a range of di-sec-alkyl acetals from ketones has been accomplished using tri-sec-alkyl orthoformate and cerium(III) trifluoromethanesulfonate. ... 1a Kocienski PJ. Protecting Groups 3rd ed.: Thieme; New ...