Journal of the American Chemical Society

Aminophenyl-2-oxazolines as local anesthetics

MT Leffler, R Adams

Index: Leffler; Adams Journal of the American Chemical Society, 1937 ,  vol. 59, p. 2252,2256            

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Citation Number: 44

Abstract

Summary 1. Several series of local anesthetics of the procaine type are described. Modifications of the general formula, NHZC~ HL! OO-X-NR~ R~, were synthesized in which (a) the alkyl groups on the nitrogen were varied while several nuclei of the type NHzC6H4COO-X-were held constant;(b) the X was a forked residue with only two carbons between the oxygen and nitrogen;(c) the X was a straight-chain residue consisting of 2, 3, ...