Tetrahedron

Organophosphorous analogues and derivatives of cleotides.: I. Phosphono-and methylphosphino analogues of aminoacyl-5'-adenilic acid

IA Natchev

Index: Natchev Tetrahedron, 1988 ,  vol. 44,  # 20  p. 6455 - 6463

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Citation Number: 7

Abstract

The organophosphorous analogues 2–7 of aminoacyl-5'-adenilic acid 1 have been synthesized by substitution of the anhydride oxygen atom with a methylene group, and of the hydroxyphosphinyl group with a methyl one. A new synthetic method has been developed for obtaining organophosphorous acids by condensation of the acidic chlorides of glycine, L- alanine and L-phenylalanine (N-acetyl derivatives, containing EtOCOCH2PO (OEt) R, ...