Tetrahedron letters

Design and synthesis of haptens for antibody catalyzed hydrolysis of organophosphorus nerve agents

PY Renard, P Vayron, F Taran, C Mioskowski

Index: Renard, Pierre-Yves; Vayron, Philippe; Taran, Frederic; Mioskowski, Charles Tetrahedron Letters, 1999 , vol. 40, # 2 p. 281 - 284

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Citation Number: 17

Abstract

Download full text in PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... Haptens bearing phosphorane and α-hydroxyphosphinate structures have been designed and synthesized for the selection of monoclonal antibodies with phosphatase like activity in order to detoxify highly toxic organophosphorus chemical weapons such as VX.