Synthesis of 2-aminofurans and 2-unsubstituted furans via carbenoid-mediated [3+ 2] cycloaddition

Y Jiang, VZY Khong, E Lourdusamy…

Index: Jiang, Yaojia; Khong, Vanessa Zhong Yue; Lourdusamy, Emmanuvel; Park, Cheol-Min Chemical Communications, 2012 , vol. 48, # 25 p. 3133 - 3135

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Citation Number: 30

Abstract

An efficient dual synthetic manifold for 2-aminofurans and 2-unsubstituted furans has been developed. The carbenoid-mediated [3+ 2] cycloaddition of copper carbenoids with enamines provides 2-amino-2, 3-dihydrofurans which serve as common intermediates for both 2-aminofurans and 2-unsubstituted furans.

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