Synthesis and dopamine receptor affinities of 1-aminoethylhetero-tetralines

…, V Tortorella, S Govoni, MD Lograno, E Daniele

Index: Perrone, R; Berardi, F; Tortorella, V; Govoni, S; Lograno, MD; Daniele, E European Journal of Medicinal Chemistry, 1991 , vol. 26, # 9 p. 869 - 874

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Citation Number: 3

Abstract

Abstract A series of 1-aminoethylhetero-tetralines 3–6, which can be considered as opened- structure analogues of previously studied dopaminergic compounds 2, were synthesized. In the binding studies, to evaluate D-1 and D-2 activity, no significant affinity was observed towards both dopaminergic receptors.