Tetrahedron Letters

Recyclable gallium (III) triflate-catalyzed [4+ 3] cycloaddition for synthesis of 2, 4-disubstituted-3H-benzo [b][1, 4] diazepines

SG Huang, HF Mao, SF Zhou, JP Zou, W Zhang

Index: Huang, Shi-Gang; Mao, Hai-Feng; Zhou, Shao-Fang; Zou, Jian-Ping; Zhang, Wei Tetrahedron Letters, 2013 , vol. 54, # 46 p. 6178 - 6180

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Citation Number: 9

Abstract

Abstract Simple and efficient Ga (OTf) 3-catalyzed [4+ 3] cycloaddition of 1, 3- diarylpropynones and o-phenylenediamines is developed for the preparation of 2, 4- disubstituted-3H-benzo [b][1, 4] diazepines. The reaction has advantages of using a green solvent, generating a minimal amount of waste, and easy catalyst recycle.

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