Pyridazine Derivatives. V. 1, 2 Some Ethers and Thioethers Derived from 3, 6-Dichloropyridazine

EA Steck, RP Brundage

Index: Steck; Brundage Journal of the American Chemical Society, 1959 , vol. 81, p. 6511,6512

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Citation Number: 10

Abstract

The detailed pharmacological evaluation of the bis-quaternary salts of 3, 6-bis- (dialkylaminoalkoxyj-pyridazines, together with kindred thioethers,“has e~ tablished~-~ that the series has novel patterns of neuromuscular blocking action. The greatest potency was found in the quaternary ammonium salts of I. Continuing interest was fostered by these results, and the present contribution relates to various ethers and thioethers which were ...