8-Chloro and 8-methylthio derivatives of 10-piperazino-10, 11-dihydrodibenzo [b, f] thiepins; New compounds and new procedures

…, Z Prošek, J Holubek, E Svátek…

Index: Jilek,Jiri; Pomykacek, Josef; Prosek, Zdenek; Holubek, Jiri; Svatek, Emil; et al Collection of Czechoslovak Chemical Communications, 1983 , vol. 48, # 3 p. 906 - 927

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Citation Number: 4

Abstract

Abstract The resolution of racemic clorothepin (Ia) was repeated and the water-soluble methanesulfonates of (S)(+)-clorothepin and (R)(-)-clorothepin were prepared which were used in recent studies of the stereoselectivity of action of this neuroleptic agent. Alkylation ...