Synthesis and Characterization of fac??Re (CO) 3??aspartic??N??monoacetic Acid: Structural Analogue of a Potential Renal Tracer, fac??99mTc (CO) 3 (ASMA)

…, M Lipowska, AT Taylor, LG Marzilli

Index: Klenc, Jeffrey; Lipowska, Malgorzata; Taylor, Andrew T.; Marzilli, Luigi G. European Journal of Inorganic Chemistry, 2012 , # 27 p. 4334 - 4341

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Citation Number: 3

Abstract

Abstract The reaction of an aminopolycarboxylate ligand, aspartic-N-monoacetic acid (ASMA), with [Re (CO) 3 (H 2 O) 3]+ was examined. The tridentate coordination of ASMA to this Re I (CO) 3 precursor yielded fac-Re (CO) 3 (ASMA) as a mixture of diastereomers. The chemistry is analogous to that of the Tc I (CO) 3 complex, which yields fac-99m Tc (CO) 3 (ASMA) under similar conditions. The formation, structure, and isomerization of fac-Re ( ...