Identification of a chromone-based retinoid containing a polyolefinic side chain via facile synthetic routes
W Sun, PJ Carroll, DR Soprano, DJ Canney
Index: Sun, Weilin; Carroll, Patrick J.; Soprano, Dianne R.; Canney, Daniel J. Bioorganic and Medicinal Chemistry Letters, 2009 , vol. 19, # 15 p. 4339 - 4342
Full Text: HTML
Citation Number: 7
Abstract
Attempts to prepare substituted chromones as novel retinoids revealed that some chromones were unstable under Wadsworth–Horner–Emmons reaction conditions. Hence, Wittig reactions were used to prepare chromone-based compounds as potential retinoids. Firstly, Wittig reagents prepared from 3-bromomethyl-chromen-4-one were reacted with olefinic-aldehydes to provide the target compounds with all-trans side chains in good yield ...
Related Articles:
Chloroperoxidase-catalyzed oxidation of conjugated dienoic esters
[Bougioukou, Despina J; Smonou, Ioulia Tetrahedron Letters, 2002 , vol. 43, # 2 p. 339 - 342]
Chloroperoxidase-catalyzed oxidation of conjugated dienoic esters
[Bougioukou, Despina J; Smonou, Ioulia Tetrahedron Letters, 2002 , vol. 43, # 2 p. 339 - 342]
Chloroperoxidase-catalyzed oxidation of conjugated dienoic esters
[Bougioukou, Despina J; Smonou, Ioulia Tetrahedron Letters, 2002 , vol. 43, # 2 p. 339 - 342]
A synthetic route to the C4 octadienic esters of trichothecenes from D-glucose
[Tulshian, Deen Bhandu; Fraser-Reid, Bert Journal of the American Chemical Society, 1981 , vol. 103, # 2 p. 474 - 475]