Synthesis of heteroarylazulenes: transition metal free coupling strategy of azulene with heterocycles
T Shoji, R Yokoyama, S Ito, M Watanabe, K Toyota…
Index: Shoji, Taku; Yokoyama, Ryuji; Ito, Shunji; Watanabe, Masataka; Toyota, Kozo; Yasunami, Masafumi; Morita, Noboru Tetrahedron Letters, 2007 , vol. 48, # 7 p. 1099 - 1103
Full Text: HTML
Citation Number: 22
Abstract
Azulene reacts with highly electrophilic trifluoromethanesulfonates of N-containing heterocycles to give 1-dihydroheteroaryl and 1, 3-bis (dihydroheteroaryl) azulene derivatives in a good yield. Treatment of the dihydroheteroarylazulene derivatives with KOH or tert-BuOK afforded 1-heteroaryl and 1, 3-bis (heteroaryl) azulenes in a good yield.
Related Articles:
[Lash, Timothy D.; Colby, Denise A.; Graham, Shelley R.; Chaney, Sun T. Journal of Organic Chemistry, 2004 , vol. 69, # 25 p. 8851 - 8864]
Über bi??und polycyclische Azulene, XLV. Die Aminometylierung des Azulens
[Muehlstaedt,M. et al. Chemische Berichte, 1961 , vol. 94, p. 808 - 811]
Über bi??und polycyclische Azulene, XLV. Die Aminometylierung des Azulens
[Muehlstaedt,M. et al. Chemische Berichte, 1961 , vol. 94, p. 808 - 811]