On the factors affecting product distribution in laccase-catalyzed oxidation of a lignin model compound vanillyl alcohol: experimental and computational evaluation

…, M Oivanen, P Karhunen, K Kruus, J Sipilä

Index: Lahtinen, Maarit; Heinonen, Petri; Oivanen, Mikko; Karhunen, Pirkko; Kruus, Kristiina; Sipilae, Jussi Organic and Biomolecular Chemistry, 2013 , vol. 11, # 33 p. 5454 - 5464

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Citation Number: 6

Abstract

Laccases (EC 1.10. 3.2) are multicopper oxidases, which can oxidize phenolic substrates by the concomitant reduction of oxygen to water. The phenolic substructures of lignin are also oxidized by laccases, resulting mainly in various polymerized products. Several model compound studies indicate that variations in the reaction media, such as the pH and the enzyme dosage used, have an impact on the observed product distribution of laccase ...