Synthesis of lipophilic crown ethers with pendant carboxylic acid groups

…, A Czech, B Son, HK Lee, RA Bartsch

Index: Czech, Bronislaw P.; Czech, Anna; Son, Byungki; Lee, Han Koo; Bartsch, Richard A. Journal of Heterocyclic Chemistry, 1986 , vol. 23, p. 465 - 471

Full Text: HTML

Citation Number: 33

Abstract

Abstract Synthetic routes to thirteen highly lipophilic crown ether carboxylic acids are described. Seven contain 12–15-membered crown ether units with four ring oxygens and are designed for lithium ion complexation. Three others possess large ring 24-crown-8, 27- crown-9, and 30-crown-10 units. Six new hydroxymethyl crown ethers are prepared as synthetic intermediates.