Competitive intramolecular hydrogen bonding in oligo (ethylene oxide) substituted quadruple hydrogen bonded systems

…, MML Nieuwenhuizen, RP Sijbesma…

Index: De Greef, Tom F.A.; Nieuwenhuizen, Marko M.L.; Sijbesma, Rint P.; Meijer Journal of Organic Chemistry, 2010 , vol. 75, # 3 p. 598 - 610

Full Text: HTML

Citation Number: 36

Abstract

A series of oligo (ethylene oxide)(oligoEO) substituted 2-ureido-pyrimidinones (UPy), differing in the number of ethylene oxide units and the length of the aliphatic spacer connecting the oligoEO side chain with the UPy group, have been prepared. It was found that variation in these structural parameters strongly influences the dimerization constant (K dim) of the UPy dimer and the association constant (K a) of UPy with 2, 7-diamido-1, 8- ...