Tetrahedron letters

Simple syntheses of cyclic polyamines using selectively N-tritylated polyamines and succinic anhydride

M Militsopoulou, N Tsiakopoulos, C Chochos…

Index: Militsopoulou, Maria; Tsiakopoulos, Nikolaos; Chochos, Christos; Magoulas, George; Papaioannou, Dionissios Tetrahedron Letters, 2002 , vol. 43, # 14 p. 2593 - 2596

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Citation Number: 14

Abstract

Treatment of selectively N-tritylated spermidine and spermine derivatives with succinic anhydride, followed by PyBrOP-mediated intramolecular amide bond formation and LiAlH4 reduction, allows for an easy and general entry to cyclic polyamine derivatives.

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