New four-component ugi-type reaction. Synthesis of heterocyclic structures containing a pyrrolo [1, 2-a][1, 4] diazepine fragment

…, SA Kutepov, AV Nikitin, AV Ivachtchenko

Index: Ilyn, Alexey P.; Trifilenkov, Andrey S.; Kuzovkova, Julia A.; Kutepov, Sergey A.; Nikitin, Alexandre V.; Ivachtchenko, Alexandre V. Journal of Organic Chemistry, 2005 , vol. 70, # 4 p. 1478 - 1481

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Citation Number: 36

Abstract

We present a convenient synthesis of novel heterocyclic structures containing pyrrolo [1, 2- a][1, 4] diazepine fragment using a novel modification of four-component Ugi condensation. We demonstrate the usefulness and versatility of the developed approach for the synthesis of variously substituted compounds and discuss the scope and limitations of the chemistry involved.