Synthesis of 2, 3-disubstituted benzo [b] selenophenes via electrophilic cyclization

T Kesharwani, SA Worlikar…

Index: Kesharwani, Tanay; Worlikar, Shilpa A.; Larock, Richard C. Journal of Organic Chemistry, 2006 , vol. 71, # 6 p. 2307 - 2312

Full Text: HTML

Citation Number: 103

Abstract

2, 3-Disubstituted benzo [b] selenophenes have been prepared by the electrophilic cyclization of various 1-(1-alkynyl)-2-(methylseleno) arenes by Br2, NBS, I2, ICl, PhSeCl, PhSeBr, and Hg (OAc) 2. This method tolerates a wide variety of functional groups, including alcohol, ester, nitrile, nitro, and silyl groups, and proceeds under exceptionally mild reaction conditions.