A new stereoselective synthesis of grandisol

K Langer, J Mattay, A Heidbreder…

Index: Langer, Klaus; Mattay, Jochen; Heidbreder, Andreas; Moeller, Manfred Liebigs Annalen der Chemie, 1992 , # 3 p. 257 - 260

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Citation Number: 9

Abstract

Abstract Grandisol (10) is stereoselectively synthesized in 9 steps, starting from commercially available 3-methyl-3-buten-1-ol (1). The key step of the synthesis is the Cu (I)- catalyzed [2+ 2]-photocycloaddition of 3 to 4a or 4b. Moreover, solvent effects on the endo/exo product ratio of the [2+ 2]-photocycloaddition are investigated.

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