Flavone-3-carboxylic acids, esters, and related compounds from. beta.-(chloroarylidene) malonates

OEO Hormi, MR Moisio, BC Sund

Index: Hormi, Osmo E. O.; Moisio, M. Riitta; Sund, B. Christian Journal of Organic Chemistry, 1987 , vol. 52, # 23 p. 5272 - 5274

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Citation Number: 13

Abstract

@-Chloroarylidenemalonates I have been transformed into p-(ary1oxy) arylidenemalonates 11. The ring closure of I1 in polyphosphoric acid leads to ethyl flavone-3-carboxylates and related compounds 111. Hydrolysis of I1 gives 8-(ary1oxy) arylidenemalonic acids V, which on treatment with concentrated sulfuric acid or trifluoroacetic acid-trifluoroacetic anhydride give flavone-3-carboxylic acids and related compounds VI.

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