A new and rapid synthesis of phospholipids

C Mcguigan

Index: McGuigan, Christopher Journal of the Chemical Society, Chemical Communications, 1986 , # 7 p. 533 - 534

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Citation Number: 16

Abstract

Reaction of 2-chloro-3-methyl-l,3,2-oxazaphosphacyclopentane with long chain alcohols gives cyclic alkyl phosphoramidites, which yield alkyl phosphoryl N-methylethanolamines on dinitrogen tetroxide oxidation and acid hydrolysis. ... Phospholipids are major components of cell membranes;' their amphipathic structure confers on such membranes a bi-layer structure.2 Phospholipids have also been implicated in a number of physiological processes,3 and their synthesis is ...