Synergistic Palladium??Catalyzed C (sp3) H Activation/C (sp3) O Bond Formation: A Direct, Step??Economical Route to Benzolactones

…, A Correa, J Gallardo??Donaire…

Index: Novak, Petr; Correa, Arkaitz; Gallardo-Donaire, Joan; Martin, Ruben Angewandte Chemie - International Edition, 2011 , vol. 50, # 51 p. 12236 - 12239

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Citation Number: 70

Abstract

In the last decade, CÀH bond-activation protocols have profoundly changed the landscape of organic synthesis through unconventional bond-disconnection strategies for the assembly of complex organic molecules.[1] Ideally, directing groups that are commonly employed in CÀH activation processes should have a dual role by assisting chelation and subsequently promoting further functionalization. The use of benzoic acids holds great promise in this ...

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