Thermal lactonization of brominated alkylidenemalonates: Synthesis of 2??buten??4??olides
R Verhé, N De Kimpe, L De Buyck…
Index: Verhe,R. et al. Bulletin des Societes Chimiques Belges, 1978 , vol. 87, p. 215 - 222
Full Text: HTML
Citation Number: 9
Abstract
Abstract Heating of dialkyl 2-bromoalkylidenemalonates in boiling xylene resulted in lactonization with formation of 2-alkoxycarbonyl-2-buten-4-olides. Bromination of dimethyl 2- phenylpropylidenemalonate with NBS in CCI 4 gave the corresponding butenolide. However, heating of the 2-bromocyclohexylidenemalonate only afforded the dehydrobromination product.
Related Articles:
Synthesis of substituted cyclopropylphosphonates by Michael Induced Ring Closure (MIRC) reactions
[Stevens, Christian V.; Van Heecke, Gino; Barbero, Carmen; Patora, Krystyna; De Kimpe, Norbert; Verhe, Roland Synlett, 2002 , # 7 p. 1089 - 1092]
Synthesis of substituted cyclopropylphosphonates by Michael Induced Ring Closure (MIRC) reactions
[Stevens, Christian V.; Van Heecke, Gino; Barbero, Carmen; Patora, Krystyna; De Kimpe, Norbert; Verhe, Roland Synlett, 2002 , # 7 p. 1089 - 1092]