Synthesis of 2, 4-Disubstituted Quinolines by Reactions of o-Isocyano-. BETA.-methoxystyrene Derivatives with Organolithiums.
K Kobayashi, K Yoneda, M Mano, O Morikawa…
Index: Kobayashi, Kazuhiro; Yoneda, Keiichi; Mano, Masaaki; Morikawa, Osamu; Konishi, Hisatoshi Chemistry Letters, 2003 , vol. 32, # 1 p. 76 - 77
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Citation Number: 15
Abstract
Quinolines are important because of their occurrence in nature,1 their biological properties,2 and their utilities as inter- mediates for the design of biologically active compounds.3 Especially 2-alkylated derivatives have been reported to exhibit notable biological activities.4 Thus, a large number of general methods for the preparation of substituted quinolines have recently been reported.5;6 In this paper we wish to describe the results of our investigation, which offer ...
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