Journal of the American Chemical Society

Novel syntheses of tetrahydropyrroloquinolines: Applications to alkaloid synthesis

AJ Peat, SL Buchwald

Index: Peat, Andrew J.; Buchwald, Stephen L. Journal of the American Chemical Society, 1996 , vol. 118, # 5 p. 1028 - 1030

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Citation Number: 113

Abstract

Two novel routes involving the intramolecular olefin insertion with a zirconium-benzyne complex, followed by a palladium-catalyzed aryl amination, have been developed for the synthesis of tetrahydropyrroloquinolines. In one approach, exemplified in the six-step total ...